hrp0092rfc4.3 | Fat Metabolism and Obesity Session | ESPE2019

Dysregulated Gene Expression Profile in Visceral Adipose Tissue of Juvenile Wistar Rats with Catch-Up Growth: Association with Fat Expansion and Metabolic Parameters

Lizárraga-Mollinedo Esther , Carreras-Badosa Gemma , Remesar Xavier , Xargay-Torrent Silvia , Mas-Parés Berta , Prats-Puig Anna , de Zegher Francis , Ibáñez Lourdes , López-Bermejo Abel , Bassols Judit

Background: Accelerated catch-up growth following intrauterine growth restriction increases the risk of developing visceral adiposity and metabolic syndrome. Animal models of growth restriction during gestation have been developed as a powerful tool to provide insight into the underlying molecular mechanisms thereof.Objective: To analyze the patterns of gene expression in the retroperitoneal adipose tissue of rats with i...

hrp0092p1-193 | Fat, Metabolism and Obesity (1) | ESPE2019

Circulating Insulin-Like Growth Factor-I Independently Predicts Blood Pressure in Apparently Healthy Children

Xargay-Torrent Sílvia , Dorado-Ceballos Estefanía , Benavides-Boixader Anna , Lizárraga-Mollinedo Esther , Mas-Parés Berta , Montesinos-Costa Mercè , Zegher Francis de , Ibáñez Lourdes , Bassols Judit , López-Bermejo Abel

Background and Objectives: In adults, discordant associations exist between insulin-like growth factor-I (IGF-I) and blood pressure with scarce reports in apparently healthy children. IGF-I levels increase during puberty in parallel to calcium and phosphorus levels. In this context, our aim is to study the association between IGF-I and blood pressure in apparently healthy children, together with the interaction of the serum calcium-phosphorus product (Ca*P...